Bioreactors and Fermenters

Bioreactors and Fermenters

Microorganisms are utilized in industry to create a scope of concoction mixes, proteins and medications – this is on the grounds that: 

They are little thus can be developed financially in fermenters on either strong or fluid media

They have a quick development rate thus can deliver expansive yields in brief timeframes

They can be hereditarily changed without hardly lifting a finger to integrate non-common results of intrigue

May probably endure surprising development conditions (for example extremophiles can develop in high temperatures or acidic conditions)

Bioreactors and Fermenters

At the point when developed in fermenters, microorganism rate of development will in the long run wind up constrained by metabolic waste items

The maturation response can be intermittently ended to recharge supplements and evacuate squanders (group culture)

On the other hand, supplement and waste dimensions can be powerfully acclimated to keep up the response inconclusively (ceaseless culture)

We offer particular Bioreactors and Fermenters for research, improvement, and creation appropriate for aging, cell culture, undeveloped cells, sustainable advancements, green growth tech, biomass, biofuel, hydrolysis and that's just the beginning. The extraordinary secluded plan of uma pharmatech machinery comforts is good with a wide assortment of compatible benchtop STR glass vessels, extending from 50ml to 20l in volume, SUB expendable vessels from 250ml to 75l and LAB/PILOT SIP in situ sterilisable bioreactor from 1l to 100l. 

Bioreactors and Fermenters

We additionally produce modern bioreactors up to 50m3, CIP in situ cleaning bioreactor, SIP/CIP process vessels, and turnkey ventures with coordinated outsider hardware and custom fit arrangements. We join long stretches of involvement in sterile procedure building with the most recent robotization and programming advances enhanced for bioprocess researchers.

Uma Pharmatech Machinery supplies a scope of institutionalized and tweaked Pilot Bioreactors and Fermenters for your microbial culture needs – bacterial or yeast just as cell culture from 20 L to 500 Liters w/v. 

Bioreactors and Fermenters

We are experts in the assembling of computerization, programming and vessels for the pharmaceutical and biotech ventures. We have an answer for all your bioprocessing/maturation needs since we comprehend bioreactors and the procedures required to make pharmaceuticals as indicated by strict cGMP rules.

Uma pharmatech machinery is a solitary source provider of particular stainless steel bioreactor and answers for address the issues of any pharmaceutical, microbial or cell aging procedure. The organization has the skill and industry information to enable clients to test procedures and settle on the correct decision of gear to guarantee the security of result and the quickest time to showcase.

Highlights

Pilot scale culture vessels are accessible in bacteriological or cell development arrangements in the accompanying sizes: 20, 30, 40, 50, 70, 80, 100, 130, 150, 200, 250, 300, 400 and 500 liter volume

Bioreactors and Fermenters

 

Driving industry parts for, gadgets, sensors, valves and gas blending, among others, offer quality without trade off

Channeling module configuration kills easygoing administrator contact

Amazing SCADA/ plc programming to at the same time deal with different bioreactors

Completely programmed in-situ disinfection with incorporated steam generator

Coordinated or outside CIP set up cleaning framework

Particular plan and interconnectivity with outer gadgets give the likelihood of individual arrangements.

Applications incorporate

Pilot-scale maturation of oxygen consuming and anaerobic microorganisms, yeasts, and growths

Cell culture of mammalian, creepy crawly and human cell lines

Immunization, monoclonal immunizer

Sustainable power sources, biofuel/biopolymer creation.

UMA PHARMATECH MACHINERY  configuration, specialist and production top notch custom Bioreactors and Fermenters up to 50 cubic meters.

Our portfolio contains an amazing scope of designing and assembling arrangements that have been coordinated to address the procedure and gear needs basic to the cell development process. Our custom arrangements meet industry best practice and nearby administrative necessities.

Also, we give broad post-retail administration and backing, including save parts, hardware redesigns, adjusting and upkeep, and client preparing.

Bioreactors and Fermenters

UPM mechanical stainless steel bioreactor are planned and fabricated for simple activity, available parts and have wellbeing as a top priority:

Clean steam, sterile gas, and item contact lines are orbitally butt welded to the most extreme degree conceivable.

Our way to deal with gear configuration is to take part in a dialog of point by point venture necessities with our clients.

We guarantee that our proposition meets the specialized procedure, time to market and business prerequisites for the consummation of an effective task.

The primary goal of Uma Pharmatech Machinery is to give our customers turn-key answers for the building and specialized administration of their tasks so they can accomplish the best targets.

UMA PHARMATECH MACHINERY will help you in obtaining and conveying to the generation plants all the important supplies, gear, and instrumentation from lab scale to creation and last detailing and assembling of the items. 

Bioreactors and Fermenters

Ability

Procedure designing (P&ID, utilitarian investigation)

Mechanical structure (vessels and funneling – 3D isometric illustrations).

Electrical and control framework configuration, programming

Channeling assembling and wiring

Authorizing and after-deals administration

Capability and Validation (cGMP, GAMP, CFR21 section 11)

Plan Qualification (DQ)

Establishment Qualification (IQ)

Operational Qualification (OQ)

Production line Acceptance Test (FAT)

Site Acceptance Test (SAT)

Execution Qualification (PQ)

Our stainless steel bioreactor guarantee long haul sterility amid medium or supplement change, aseptic examining, air circulation, venting or exchange, exceedingly exact temperature control, stirrers adjusted to give ideal oxygen exchange rates and cell densities and dead sans leg plan.

Applications

Microbial and cell development applications from R&D to mechanical scale creation of immunizations

Restorative proteins

Monoclonal antibodies

Fixings

Chemicals and biomass

Blood subordinates (Factors VIII and IX, immunoglobulin, egg whites, and so forth.)

Immuno-biologicals (Monoclonal Antibodies, Interleukins, Interferon)

Hormones (Insulin, Growth hormone, and so on.)

Against malignant growth operators

Microbial and viral vaccines.s and other

The autoclavable fermentors are borosilicate glass
body with stainless flanges at the top and bottom with
all necessary ports made of SS-316L. Agitation is through a mechanically coupled agitator which can run from 0~1200 RPM. The in-place sterilizable is made of complete stainles steel SS316L wetted parts and jacket made of SS-304. The system is available as fully manual or automatic system. The automatic system provides automatic with RPM, Temp, pH, DO, Foam etc.
PLC based systems with Independent PID control options.

Hardened Steel Bioreactors

The Uma pharmatech machinery Pilot fermenter and bioreactor extend is isolated into a microbial range and a cell culture scope of volumes. The microbial Sterilizable-In-Place bioreactor and fermenter arrive in an all out volume of 20 L, 40 L, 70 L and 140 L. The cell culture Sterilizable-In-Place bioreactor and fermenter arrive in a complete volume of 30 L, 60 L and 130 L. The fundamental contrast between these two lines is the viewpoint proportion of the bioreactors. The microbial bioreactor have a perspective proportion of 3.0 at all out volume while the cell culture bioreactor have a viewpoint proportion of 1.5 at all out volume. The little impression ensures that the insignificant measure of floor space is involved by the bioreactor.  All bioreactor are completely recorded for cGMP use and are provided with a broad documentation bundle to help approval.

Bioreactors and Fermenters

Bioreactors and Fermenters

A wide scope of standard modules and standard packs is accessible to modify the stainless steel bioreactor to your particular requests. A wide scope of extra packs is accessible. The standard packs incorporate weight control, weight control, twofold gas gulf lines, CIP modules, biomass sensors, perfusion stainless steel bioreactor and considerably more.

Control

Uma pharmatech machinery offers a decision of ez-Control and I-Control process control stainless steel bioreactor. The I-Control can be provided with a DeltaV controller, an Allen Bradley or a Siemens PLC. All I-Control stainless steel bioreactor bolster computerized Sterilization and Cleaning strategies.

Bioreactors and Fermenters

Highlights

• Easy to clean mirror cleaned outside completion

• Electropolished completion of all parts in contact with the way of life (Ra < 0.4 µm) to permit proficient clean set up

• Modular structure enables simple adjustment to changing procedure requests

• Magnetically coupled fomenter for significant serenity

• cGMP consistent plan and documentation rearranges approval

• Compact structure diminishes floor space

• Open edge development gives simple access for upkeep and activity

Applications

• Scale-up studies

• Medium streamlining

• Process streamlining

• Small scale creation

• Microbial and Cell culture

• Batch, Fed-Batch, Perfusion and Continuous development